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- Live5/17/2026, 4:35:28 PM
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{ "scope": "macaque, neural tracer injections", "claim_text": "Up to 30% of corticostriatal projections in macaques arise from contralateral motor, prefrontal, and cingulate cortex, providing an anatomical substrate for bilateral signaling that bypasses the assumed unilateral parallel-loop model.", "raw_fields": { "n": 0, "doi": "10.1523/jneurosci.0071-22.2022", "claim": "Up to 30% of corticostriatal projections in macaques arise from contralateral motor, prefrontal, and cingulate cortex, providing an anatomical substrate for bilateral signaling that bypasses the assumed unilateral parallel-loop model.", "cite_key": "Borra2022", "evidence": "Tracer injections into striatum of macaques demonstrated robust crossed corticostriatal projections originating selectively from motor, prefrontal and cingulate areas — supplementing the canonical ipsilateral parallel circuits.", "effect_size": "up to 30% of total labeled cells from contralateral cortex", "text_access": "abstract_only", "study_system": "macaque, neural tracer injections", "source_cluster_id": "cluster_06", "replication_status": "replication_unknown", "claim_source_sentence": "The results showed that crossed CSt projections to the caudate and the putamen can be relatively robust (up to 30% of total labeled cells).", "replication_evidence_dois": [], "effect_size_source_sentence": "The results showed that crossed CSt projections to the caudate and the putamen can be relatively robust (up to 30% of total labeled cells)." }, "section_id": "section_07", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json", "effect_size": "up to 30% of total labeled cells from contralateral cortex", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-07", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-5d212b112170" ], "source_span": "The results showed that crossed CSt projections to the caudate and the putamen can be relatively robust (up to 30% of total labeled cells).", "study_system": "macaque, neural tracer injections", "evidence_refs": [ { "ref": "paper:paper-5d212b112170" } ], "section_title": "Parallel Loop Channels: Motor, Limbic, Associative, and Beyond the Classic Three", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "Tracer injections into striatum of macaques demonstrated robust crossed corticostriatal projections originating selectively from motor, prefrontal and cingulate areas — supplementing the canonical ipsilateral parallel circuits.", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-07", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_07_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }