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- Live5/17/2026, 4:35:28 PM
457befc3f4a2Content snapshot
{ "scope": "mouse, ACC-to-V1 projection neurons, in vivo neural recording", "claim_text": "V1-projecting anterior cingulate cortex (ACC) neurons in adult preterm-born mice show hyper-responsiveness to rewarded cues, resembling adolescent-like processing, indicating altered long-range prefrontal-to-sensory cortical circuit function after preterm birth.", "raw_fields": { "n": 0, "doi": "10.1101/2024.11.26.625455", "claim": "V1-projecting anterior cingulate cortex (ACC) neurons in adult preterm-born mice show hyper-responsiveness to rewarded cues, resembling adolescent-like processing, indicating altered long-range prefrontal-to-sensory cortical circuit function after preterm birth.", "cite_key": "McCoy2024", "evidence": "Adult preterm-born mice were trained on a visual discrimination task; neural activity was recorded in V1 and V1-projecting ACC neurons (long-range prefrontal-to-V1 projection neurons) using in vivo imaging or electrophysiology.", "effect_size": "", "text_access": "abstract_only", "study_system": "mouse, ACC-to-V1 projection neurons, in vivo neural recording", "argument_role": "supporting", "replication_status": "novel", "claim_source_sentence": "Using, we found that the neurons in the primary visual cortex (V1) and the V1-projecting prefrontal anterior cingulate cortex (ACC) are hyper-responsive to the reward, reminiscent of cue processing in adolescence.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "" }, "section_id": "section_06", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json", "effect_size": "", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons", "source_kind": "review_finding", "source_path": "evidence/section_06_evidence_package.json", "source_refs": [ "paper:paper-ba5b2b3db5fc" ], "source_span": "Using, we found that the neurons in the primary visual cortex (V1) and the V1-projecting prefrontal anterior cingulate cortex (ACC) are hyper-responsive to the reward, reminiscent of cue processing in adolescence.", "study_system": "mouse, ACC-to-V1 projection neurons, in vivo neural recording", "evidence_refs": [ { "ref": "paper:paper-ba5b2b3db5fc" } ], "section_title": "6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Adult preterm-born mice were trained on a visual discrimination task; neural activity was recorded in V1 and V1-projecting ACC neurons (long-range prefrontal-to-V1 projection neurons) using in vivo imaging or electrophysiology.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "novel", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }