Details

scope
mouse visual cortex, in vitro optogenetics
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
Coherent gamma at 30 Hz across up to 850 μm; dependent on SOM, not PV activity
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse visual cortex, in vitro optogenetics
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Optogenetic patterned illumination in acute brain slices of mouse visual cortex with PV and SOM manipulations
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
single study
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (6)
claim_text
A circuit composed of L2/3 pyramidal cells and SOM interneurons generates narrow-band 30 Hz gamma oscillations that are coherent across cortical space up to 850 μm and dependent on SOM but not PV neuron activity, challenging the view that PV cells are the sole drivers of gamma
raw_fields
{
  "n": 0,
  "doi": "10.7554/elife.28569",
  "claim": "A circuit composed of L2/3 pyramidal cells and SOM interneurons generates narrow-band 30 Hz gamma oscillations that are coherent across cortical space up to 850 μm and dependent on SOM but not PV neuron activity, challenging the view that PV cells are the sole drivers of gamma",
  "evidence": "Optogenetic patterned illumination in acute brain slices of mouse visual cortex with PV and SOM manipulations",
  "effect_size": "Coherent gamma at 30 Hz across up to 850 μm; dependent on SOM, not PV activity",
  "text_access": "fulltext",
  "study_system": "mouse visual cortex, in vitro optogenetics",
  "replication_status": "single study",
  "claim_source_sentence": "The network oscillations generated here are stimulus size-dependent, coherent across cortical space, narrow band (30 Hz), and depend on SOM neuron but not parvalbumin (PV) neuron activity. Gamma oscillations generated in separate cortical locations exhibited high coherence as far apart as 850 μm, and lateral gamma entrainment depended on SOM neuron activity.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Gamma oscillations generated in separate cortical locations exhibited high coherence as far apart as 850 μm, and lateral gamma entrainment depended on SOM neuron activity."
}
source_refs
[
  "paper:paper-de315a7499ba"
]
source_span
The network oscillations generated here are stimulus size-dependent, coherent across cortical space, narrow band (30 Hz), and depend on SOM neuron but not parvalbumin (PV) neuron activity. Gamma oscillations generated in separate cortical locations exhibited high coherence as far apart as 850 μm, and lateral gamma entrainment depended on SOM neuron activity.
evidence_refs
[
  {
    "ref": "paper:paper-de315a7499ba"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.