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- Live5/17/2026, 4:35:28 PM
8287dbae4d46Content snapshot
{ "scope": "mouse hippocampal CA1", "claim_text": "Fast-spiking PV basket cells show target-selective inhibition patterns that depend on the projection target of postsynaptic pyramidal cells, suggesting that FS output properties serve specific circuit-level computations beyond simple blanket inhibition.", "raw_fields": { "n": 0, "doi": "10.1016/j.neuron.2014.03.034", "claim": "Fast-spiking PV basket cells show target-selective inhibition patterns that depend on the projection target of postsynaptic pyramidal cells, suggesting that FS output properties serve specific circuit-level computations beyond simple blanket inhibition.", "evidence": "Paired recordings revealed heterogeneous PVBC-PC microcircuits with output channel-specific connectivity patterns.", "effect_size": "selective inhibition of amygdala-projecting PCs; selective excitation from PFC-projecting PCs", "text_access": "fulltext", "study_system": "mouse hippocampal CA1", "replication_status": "replication_unknown", "claim_source_sentence": "PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs but receiving preferential excitation from the prefrontal cortex-projecting PCs.", "replication_evidence_dois": [], "effect_size_source_sentence": "PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs." }, "section_id": "section_05_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json", "effect_size": "selective inhibition of amygdala-projecting PCs; selective excitation from PFC-projecting PCs", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-05", "source_kind": "review_finding", "source_path": "evidence/section_05_evidence_package.json", "source_refs": [ "paper:paper-722a8aa86ab1" ], "source_span": "PVBCs further segregated among deep PCs, preferentially innervating the amygdala-projecting PCs but receiving preferential excitation from the prefrontal cortex-projecting PCs.", "study_system": "mouse hippocampal CA1", "evidence_refs": [ { "ref": "paper:paper-722a8aa86ab1" } ], "section_title": "Intrinsic Electrophysiology: The Fast-Spiking Phenotype and Its Variants", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Paired recordings revealed heterogeneous PVBC-PC microcircuits with output channel-specific connectivity patterns.", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-05", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }