Details
- scope
- Disc1 truncation mouse model, prelimbic cortex
- claim_text
- Truncated Disc1 mice show reduced PV fast-spiking interneuron numbers, fewer excitatory inputs, fewer release sites on targets, and impaired theta and low-gamma synchrony in prelimbic cortex correlating with depression-related behavior
- section_id
- section_10_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- effect_size
- Theta and low-gamma synchrony in prelimbic cortex inversely correlated with behavioral despair
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-10
- source_kind
- review_finding
- source_path
- evidence/section_10_evidence_package.json
- source_span
- The number of FS-INs is reduced, they receive fewer excitatory inputs, and form fewer release sites on targets.
- study_system
- Disc1 truncation mouse model, prelimbic cortex
- section_title
- Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony
- evidence_summary
- Truncated Disc1 mice show reduced PV fast-spiking interneuron numbers, fewer excitatory inputs, fewer release sites on targets, and impaired theta and low-gamma synchrony in prelimbic cortex correlating with depression-related behavior
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-10
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.7554/elife.04979", "claim": "Truncated Disc1 mice show reduced PV fast-spiking interneuron numbers, fewer excitatory inputs, fewer release sites on targets, and impaired theta and low-gamma synchrony in prelimbic cortex correlating with depression-related behavior", "evidence": "Truncated Disc1 mice show reduced PV fast-spiking interneuron numbers, fewer excitatory inputs, fewer release sites on targets, and impaired theta and low-gamma synchrony in prelimbic cortex correlating with depression-related behavior", "effect_size": "Theta and low-gamma synchrony in prelimbic cortex inversely correlated with behavioral despair", "text_access": "fulltext", "study_system": "Disc1 truncation mouse model, prelimbic cortex", "replication_status": "replication_unknown", "claim_source_sentence": "The number of FS-INs is reduced, they receive fewer excitatory inputs, and form fewer release sites on targets.", "replication_evidence_dois": [], "effect_size_source_sentence": "Theta and low-gamma synchrony in the prelimbic cortex (PrlC) is impaired in Disc1 mice and inversely correlated with the extent of behavioural despair." }- source_refs
[ "paper:paper-d9270b4444dd" ]
- evidence_refs
[ { "ref": "paper:paper-d9270b4444dd" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }