Thalamic basal ganglia relay nuclei VA, VL, and MD project to distinct prefront…

{
  "n": 0,
  "doi": "10.1523/jneurosci.22-18-08117.2002",
  "claim": "Thalamic basal ganglia relay nuclei VA, VL, and MD project to distinct prefrontal targets: VL to caudal motor areas, VA to rostral premotor and cingulate areas, and MD to dorsolateral and orbital prefrontal cortices.",
  "cite_key": "McFarland2002",
  "evidence": "Anterograde and bidirectional tracer injections in Macaque demonstrated that thalamic relays of basal ganglia output target topographically distinct frontal cortical areas while also forming nonreciprocal feedforward projections to higher cortical areas.",
  "effect_size": "3 thalamic relay nuclei to 3 frontal target zones",
  "text_access": "abstract_only",
  "study_system": "Macaque monkey thalamocortical tract tracing",
  "source_cluster_id": "cluster_06",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "VL projections target caudal motor areas (primary, supplementary, and caudal premotor areas), whereas VA projections target more rostral premotor areas (including cingulate and presupplementary motor areas) and MD projects to dorsolateral and orbital prefrontal cortices.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.21-02-00700.2001",
    "10.1126/science.7939688"
  ],
  "effect_size_source_sentence": "VL projections target caudal motor areas (primary, supplementary, and caudal premotor areas), whereas VA projections target more rostral premotor areas (including cingulate and presupplementary motor areas) and MD projects to dorsolateral and orbital prefrontal cortices."
}

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  "paper:paper-1d6c52ded149"
]

VL projections target caudal motor areas (primary, supplementary, and caudal premotor areas), whereas VA projections target more rostral premotor areas (including cingulate and presupplementary motor areas) and MD projects to dorsolateral and orbital prefrontal cortices.

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Anterograde and bidirectional tracer injections in Macaque demonstrated that thalamic relays of basal ganglia output target topographically distinct frontal cortical areas while also forming nonreciprocal feedforward projections to higher cortical areas.