In rat frontal cortex layer 5, corticopontine and crossed-corticostriatal pyram…

In rat frontal cortex layer 5, corticopontine and crossed-corticostriatal pyramidal cells form selective recurrent connections with low-threshold-spiking interneuron subtypes, while fast-spiking interneurons make non-projection-specific connections to both pyramidal classes.

{
  "n": 0,
  "doi": "10.1093/cercor/bhx276",
  "claim": "In rat frontal cortex layer 5, corticopontine and crossed-corticostriatal pyramidal cells form selective recurrent connections with low-threshold-spiking interneuron subtypes, while fast-spiking interneurons make non-projection-specific connections to both pyramidal classes.",
  "cite_key": "Morishima2017",
  "evidence": "Multiple whole-cell recordings of identified PT-like and IT-like layer-5 pyramidal cells with LTS and FS GABAergic cells in rat frontal cortex slice.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "rat (frontal cortex slice multi-patch)",
  "source_cluster_id": "cluster_02",
  "replication_status": "replicated",
  "claim_source_sentence": "In this study, we found that the 2 PC subtypes in L5 selectively make recurrent connections with LTS cells.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.0011-12.2012",
    "10.1093/cercor/bhv124"
  ],
  "effect_size_source_sentence": null
}

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