Version history

{
  "scope": "spiking model of auditory cortex",
  "claim_text": "Auditory-cortex spiking model with three interneuron classes shows that VIP-mediated disinhibition shapes context-dependent responses and explains experience-dependent plasticity.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_92",
    "doi": "10.1371/journal.pcbi.1008016",
    "pmid": "32716912",
    "year": "2020",
    "claim": "Auditory-cortex spiking model with three interneuron classes shows that VIP-mediated disinhibition shapes context-dependent responses and explains experience-dependent plasticity.",
    "pmcid": "PMC7410340",
    "title": "A circuit model of auditory cortex.",
    "authors": "Park Y, Geffen MN.",
    "journal": "PLoS computational biology",
    "cite_key": "Park2020",
    "evidence": "Conductance-based spiking circuit; perturbation of VIP→SST synapse alters predicted tuning shifts.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "spiking model of auditory cortex",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 91,
    "claim_source_sentence": "The three-unit model was developed to reproduce the compensating mechanisms of the single-unit model: PV suppression results in constant disinhibition for repeated tones, and SST suppression results in a compensating effect from PVs before adaptation that weakens as adaptation strengthens.",
    "replication_evidence_dois": [
      "10.7554/elife.55130",
      "10.1523/jneurosci.1369-21.2021",
      "10.1038/s41598-017-01830-0",
      "10.1371/journal.pcbi.1013306",
      "10.1016/j.neuron.2021.11.016"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-72a15d353d01"
  ],
  "source_span": "The three-unit model was developed to reproduce the compensating mechanisms of the single-unit model: PV suppression results in constant disinhibition for repeated tones, and SST suppression results in a compensating effect from PVs before adaptation that weakens as adaptation strengthens.",
  "study_system": "spiking model of auditory cortex",
  "evidence_refs": [
    {
      "ref": "paper:paper-72a15d353d01"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Conductance-based spiking circuit; perturbation of VIP→SST synapse alters predicted tuning shifts.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}