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- Live5/17/2026, 4:35:28 PM
f37ad4738752Content snapshot
{ "scope": "mammal neocortex", "claim_text": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.", "raw_fields": { "n": 10, "doi": "10.1016/j.neuron.2018.09.001", "year": "2018", "claim": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.", "title": null, "journal": "Neuron", "cite_key": "Abs2018", "evidence": "Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons", "effect_size": "0.5 ms", "text_access": "fulltext", "first_author": "Abs", "study_system": "mammal neocortex", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Abs, Poorthuis, Apelblat", "replication_status": "replication_unknown", "_source_cluster_index": 14, "claim_source_sentence": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.", "replication_evidence_dois": [], "effect_size_source_sentence": "The chosen irradiance (gray lines, 45 mW/mm 2 ) elicited 1.2 action potentials per pulse (0.5 ms, n = 10). (C) Average IPSCs in ChR-2 negative L1 INs (gray, n = 12), L2/3 PNs (black, n = 24), and L2/3 INs (red, n = 11). (D) Comparison of L1 NDNF-IN-mediated IPSCs in the different postsynaptic populations." }, "section_id": "section_13", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "effect_size": "0.5 ms", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-13-conclusion", "source_kind": "review_finding", "source_path": "evidence/section_13_evidence_package.json", "source_refs": [ "paper:paper-cddfd665bb4c" ], "source_span": "In particular, compared to similar experiments on PV-, SST-, and VIP-INs in somatosensory cortex ( Wall et al., 2016 ), our results indicate that L1 NDNF-INs receive input from a larger range of brain areas encoding contextual, top-down information.", "study_system": "mammal neocortex", "evidence_refs": [ { "ref": "paper:paper-cddfd665bb4c" } ], "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Learning-Related Plasticity in Dendrite-Targeting Layer 1 Interneurons", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }