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- Live5/17/2026, 4:35:28 PM
39b292aa1d72Content snapshot
{ "scope": "non-human primate, model proposal grounded in anatomical and electrophysiological evidence", "claim_text": "The hyperdirect cortico-subthalamic-pallidal pathway delivers powerful excitatory drive from motor cortex to GPi/SNr with shorter conduction latency than via the striatum, providing the substrate for a 'center-surround' selection model.", "raw_fields": { "n": 0, "doi": "10.1016/s0168-0102(02)00027-5", "claim": "The hyperdirect cortico-subthalamic-pallidal pathway delivers powerful excitatory drive from motor cortex to GPi/SNr with shorter conduction latency than via the striatum, providing the substrate for a 'center-surround' selection model.", "cite_key": "Nambu2002", "evidence": "", "effect_size": "hyperdirect conduction faster than striatal pathway; powerful excitation", "text_access": "abstract_only", "study_system": "non-human primate, model proposal grounded in anatomical and electrophysiological evidence", "source_cluster_id": "cluster_04", "replication_status": "replicated", "claim_source_sentence": "The cortico-subthalamo-pallidal 'hyperdirect' pathway conveys powerful excitatory effects from the motor-related cortical areas to the globus pallidus, bypassing the striatum, with shorter conduction time than effects conveyed through the striatum.", "replication_evidence_dois": [ "10.1523/jneurosci.4682-05.2006", "10.1523/jneurosci.4674-12.2013" ], "effect_size_source_sentence": "The cortico-subthalamo-pallidal 'hyperdirect' pathway conveys powerful excitatory effects from the motor-related cortical areas to the globus pallidus, bypassing the striatum, with shorter conduction time than effects conveyed through the striatum." }, "section_id": "section_04", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json", "effect_size": "hyperdirect conduction faster than striatal pathway; powerful excitation", "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-04", "source_kind": "review_finding", "source_path": "evidence/section_04_evidence_package.json", "source_refs": [ "paper:paper-0f022815234e" ], "source_span": "The cortico-subthalamo-pallidal 'hyperdirect' pathway conveys powerful excitatory effects from the motor-related cortical areas to the globus pallidus, bypassing the striatum, with shorter conduction time than effects conveyed through the striatum.", "study_system": "non-human primate, model proposal grounded in anatomical and electrophysiological evidence", "evidence_refs": [ { "ref": "paper:paper-0f022815234e" } ], "section_title": "Striatal Output Pathways: Direct, Indirect, and Beyond", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-04", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }