Details
- scope
- vip-interneurons
- claim_text
- Individual SCN VIP neurons can generate intrinsic, nondeterministic circadian rhythms even when isolated; population coupling via VIP signaling drives coherent ensemble rhythms.
- section_id
- section_09
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-09-cross-areas
- source_kind
- review_finding
- source_path
- evidence/section_09_evidence_package.json
- section_title
- VIP Interneurons Across Brain Regions
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- unevaluated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-09-cross-areas
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- raw_fields
{ "n": null, "doi": "10.1073/pnas.0902768106", "year": 2009, "claim": "Individual SCN VIP neurons can generate intrinsic, nondeterministic circadian rhythms even when isolated; population coupling via VIP signaling drives coherent ensemble rhythms.", "title": null, "region": "SCN", "cite_key": "Webb2009", "effect_size": null, "text_access": "abstract_only", "conflict_flag": false, "fig_table_ref": null, "_source_cluster": "cluster_08_brain_regions", "evidence_gap_flag": false, "unreplicated_flag": false, "replication_status": null, "_source_cluster_index": 46, "claim_source_sentence": "Circadian rhythms are modeled as reliable and self-sustained oscillations generated by single cells. The mammalian suprachiasmatic nucleus (SCN) keeps near 24-h time in vivo and in vitro, but the identity of the individual cellular pacemakers is unknown. We tested the hypothesis that circadian cycling is intrinsic to a unique class of SCN neurons by measuring firing rate or Period2 gene expression" }- source_refs
[ "paper:paper-06cb74795da1" ]
- source_span
Circadian rhythms are modeled as reliable and self-sustained oscillations generated by single cells. The mammalian suprachiasmatic nucleus (SCN) keeps near 24-h time in vivo and in vitro, but the identity of the individual cellular pacemakers is unknown. We tested the hypothesis that circadian cycling is intrinsic to a unique class of SCN neurons by measuring firing rate or Period2 gene expression
- evidence_refs
[ { "ref": "paper:paper-06cb74795da1" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }