Version history

{
  "scope": "biophysical L1 interneuron subtype models",
  "claim_text": "Single-cell biophysical models of four layer 1 interneuron subtypes (including VIP+, NDNF+) reproduce dominant electrophysiological features and reveal differential dendritic disinhibitory routing.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_80",
    "doi": "10.1523/jneurosci.1876-22.2023",
    "pmid": "36931710",
    "year": "2023",
    "claim": "Single-cell biophysical models of four layer 1 interneuron subtypes (including VIP+, NDNF+) reproduce dominant electrophysiological features and reveal differential dendritic disinhibitory routing.",
    "pmcid": "PMC10168018",
    "title": "Mechanisms of Dominant Electrophysiological Features of Four Subtypes of Layer 1 Interneurons.",
    "authors": "Meng JH, Schuman B, Rudy B, Wang XJ.",
    "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
    "cite_key": "Meng2023",
    "evidence": "Conductance-based models fit to in vitro ephys; intrinsic differences predict layer-specific disinhibitory effects.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "biophysical L1 interneuron subtype models",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 79,
    "claim_source_sentence": "Keywords: electrophysiology, interneurons, irregularity, layer 1, single-cell modeling, VIP cells status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2022 Sep 29; Revised 2023 Feb 1; Accepted 2023 Feb 26.",
    "replication_evidence_dois": [
      "10.1016/j.neuron.2023.11.006",
      "10.1101/2025.05.13.653877",
      "10.1101/2024.09.30.615819",
      "10.1016/j.neuron.2018.03.037",
      "10.1162/netn_a_00427"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-6ea5df1d31f1"
  ],
  "source_span": "Keywords: electrophysiology, interneurons, irregularity, layer 1, single-cell modeling, VIP cells status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2022 Sep 29; Revised 2023 Feb 1; Accepted 2023 Feb 26.",
  "study_system": "biophysical L1 interneuron subtype models",
  "evidence_refs": [
    {
      "ref": "paper:paper-6ea5df1d31f1"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Conductance-based models fit to in vitro ephys; intrinsic differences predict layer-specific disinhibitory effects.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}