Details

scope
Mouse, in vivo two-photon imaging of medial frontal (A24b/M2) axons in V1 L1 during visually guided behavior
claim_text
Top-down A24b/M2 axons projecting to L1 of mouse V1 are recruited during visually guided behavior but their activity is more tightly linked to licking and reward than to enhancement of sensory coding.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
Qualitative: A24b/M2-V1 activity correlates with licking and reward modulation rather than with sensory-coding enhancement.
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
We observe that while A24b/M2-V1are recruited under these conditions, this is not linked to enhancement of neural or behavioral measures of sensory coding.
study_system
Mouse, in vivo two-photon imaging of medial frontal (A24b/M2) axons in V1 L1 during visually guided behavior
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
In vivo two-photon imaging of A24b/M2 axons in V1 L1 while mice performed a go/no-go visual discrimination task.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2022.110932",
  "claim": "Top-down A24b/M2 axons projecting to L1 of mouse V1 are recruited during visually guided behavior but their activity is more tightly linked to licking and reward than to enhancement of sensory coding.",
  "cite_key": "Broom2022",
  "evidence": "In vivo two-photon imaging of A24b/M2 axons in V1 L1 while mice performed a go/no-go visual discrimination task.",
  "effect_size": "Qualitative: A24b/M2-V1 activity correlates with licking and reward modulation rather than with sensory-coding enhancement.",
  "text_access": "abstract_only",
  "study_system": "Mouse, in vivo two-photon imaging of medial frontal (A24b/M2) axons in V1 L1 during visually guided behavior",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "We observe that while A24b/M2-V1are recruited under these conditions, this is not linked to enhancement of neural or behavioral measures of sensory coding.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Instead, A24b/M2-V1activity is associated with licking behavior, modulated by reward, and biased toward the sensory cortical hemisphere representing the stimulus currently being discriminated."
}
source_refs
[
  "paper:paper-7339844accc7"
]
evidence_refs
[
  {
    "ref": "paper:paper-7339844accc7"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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