Details
- scope
- Scn1a+/- mouse cortex, developmental trajectory
- claim_text
- Fast-spiking interneuron dysfunction in Scn1a+/- mice is transient during a critical developmental window, with recovery by P35, challenging the view of permanent PV cell impairment.
- section_id
- section_02_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- effect_size
- transient dysfunction window; recovery by P35
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-02
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- source_span
- A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.
- study_system
- Scn1a+/- mouse cortex, developmental trajectory
- section_title
- Molecular Identity and Transcriptomic Taxonomy
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- contested
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-02
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/JNEUROSCI.0193-18.2018", "claim": "Fast-spiking interneuron dysfunction in Scn1a+/- mice is transient during a critical developmental window, with recovery by P35, challenging the view of permanent PV cell impairment.", "evidence": "", "effect_size": "transient dysfunction window; recovery by P35", "text_access": "abstract_only", "study_system": "Scn1a+/- mouse cortex, developmental trajectory", "replication_status": "contested", "claim_source_sentence": "A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome.", "replication_evidence_dois": [ "10.1073/pnas.1411131111" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-26eb18eb4bf8" ]
- evidence_refs
[ { "ref": "paper:paper-26eb18eb4bf8" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }