Version history

{
  "scope": "compartmental hippocampal model of SWR-induced PV dendritic spikes",
  "claim_text": "A compartmental model shows sharp-wave ripple doublets induce complex dendritic spikes in PV interneurons, complementing VIP-mediated disinhibition during memory consolidation.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_157",
    "doi": "10.1038/s41467-022-34520-1",
    "pmid": "36344570",
    "year": "2022",
    "claim": "A compartmental model shows sharp-wave ripple doublets induce complex dendritic spikes in PV interneurons, complementing VIP-mediated disinhibition during memory consolidation.",
    "pmcid": "PMC9640570",
    "title": "Sharp-wave ripple doublets induce complex dendritic spikes in parvalbumin interneurons in vivo",
    "authors": "Judák L, Chiovini B, Juhász G, Pálfi D, Mezriczky Z, Szadai Z, Katona G, Szmola B, Ócsai K, Martinecz B, Mihály A, Dénes Á, Kerekes B, Szepesi Á, Szalay G, Ulbert I, Mucsi Z, Roska B, Rózsa B.",
    "journal": "Nature Communications",
    "cite_key": "Judak2022",
    "evidence": "Authors developed a compartmental hippocampal model of SWR-induced PV dendritic spikes consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.",
    "vip_role": "oscillations",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "compartmental hippocampal model of SWR-induced PV dendritic spikes",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 156,
    "claim_source_sentence": "We demonstrate the existence of SPW-R-associated, branch-specific, local dSpikes and their computational role in basal dendrites of hippocampal PV+ interneurons in awake animals.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-0035d9e59c29"
  ],
  "source_span": "We demonstrate the existence of SPW-R-associated, branch-specific, local dSpikes and their computational role in basal dendrites of hippocampal PV+ interneurons in awake animals.",
  "study_system": "compartmental hippocampal model of SWR-induced PV dendritic spikes",
  "evidence_refs": [
    {
      "ref": "paper:paper-0035d9e59c29"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Authors developed a compartmental hippocampal model of SWR-induced PV dendritic spikes consistent with the cluster's canonical VIP→SST→pyramidal disinhibitory architecture.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}