- raw_fields
{
"n": 0,
"doi": "10.1523/JNEUROSCI.0963-17.2017",
"claim": "Detecting ISN regime in cortex requires large-scale perturbation of the inhibitory population; reduced models fail to predict responses in realistic networks",
"evidence": "Simulated activity perturbations in cortical networks of increasing realism",
"effect_size": "large proportion of inhibitory network must be perturbed to reliably detect ISN",
"text_access": "fulltext",
"study_system": "computational cortical network models, varying complexity",
"replication_status": "replication_unknown",
"claim_source_sentence": "We reexamined this question by investigating how cortical network models consisting of many neurons behave after perturbations and found that results obtained from reduced network models fail to predict responses to perturbations in more realistic networks.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Our models predict that a large proportion of the inhibitory network must be perturbed to reliably detect an ISN regime robustly in cortex."
}- source_refs
[
"paper:paper-5135d667ceac"
]
- source_span
We reexamined this question by investigating how cortical network models consisting of many neurons behave after perturbations and found that results obtained from reduced network models fail to predict responses to perturbations in more realistic networks.
- evidence_refs
[
{
"ref": "paper:paper-5135d667ceac"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}