- claim_text
Optogenetic dissection of BNST projections in mice shows that distinct downstream pathways assemble separable features of the anxious behavioral state — anxiogenic and anxiolytic outputs map onto different BNST efferents — providing the modern circuit basis for BNST diversification of anxiety.
- raw_fields
{
"n": null,
"doi": "10.1038/nature12018",
"claim": "Optogenetic dissection of BNST projections in mice shows that distinct downstream pathways assemble separable features of the anxious behavioral state — anxiogenic and anxiolytic outputs map onto different BNST efferents — providing the modern circuit basis for BNST diversification of anxiety.",
"cite_key": "Kim2013",
"evidence": "fulltext_body",
"effect_size": null,
"text_access": "fulltext",
"study_system": null,
"source_cluster_id": "cluster_08",
"replication_status": "unreplicated",
"claim_source_sentence": "Behavioural states in mammals, such as the anxious state, are characterized by several features that are coordinately regulated by diverse nervous system outputs, ranging from behavioural choice patterns to changes in physiology (in anxiety, exemplified respectively by risk-avoidance and respiratory rate alterations).",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-6f67b05c2774"
]
- source_span
Behavioural states in mammals, such as the anxious state, are characterized by several features that are coordinately regulated by diverse nervous system outputs, ranging from behavioural choice patterns to changes in physiology (in anxiety, exemplified respectively by risk-avoidance and respiratory rate alterations).
- evidence_refs
[
{
"ref": "paper:paper-6f67b05c2774"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}