Details

scope
rats, multi-site recording in GPe during Stop-signal task with juxtacellular labelling
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
effect_size
Arky Stop responses earlier and stronger than Proto; selective for Stop cues
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-05
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
Here we show that, consistent with this hypothesis, Arky cell activity is selectively enhanced by the Stop! cue, at just the right time to be responsible for Str suppression on correct Stop trials.
study_system
rats, multi-site recording in GPe during Stop-signal task with juxtacellular labelling
section_title
Pallidal Organization and the Disinhibition Principle
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-05
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
claim_text
During a Stop-signal task, arkypallidal neurons show earlier, stronger Stop responses than prototypic neurons and are selectively responsive to Stop cues, supporting a two-step pause-then-cancel model where STN-SNr pauses preparation and arkypallidal projections cancel ongoing striatal Go activity.
raw_fields
{
  "n": 0,
  "doi": "10.1016/j.neuron.2015.12.017",
  "claim": "During a Stop-signal task, arkypallidal neurons show earlier, stronger Stop responses than prototypic neurons and are selectively responsive to Stop cues, supporting a two-step pause-then-cancel model where STN-SNr pauses preparation and arkypallidal projections cancel ongoing striatal Go activity.",
  "cite_key": "Mallet2016",
  "evidence": "",
  "effect_size": "Arky Stop responses earlier and stronger than Proto; selective for Stop cues",
  "text_access": "fulltext",
  "study_system": "rats, multi-site recording in GPe during Stop-signal task with juxtacellular labelling",
  "source_cluster_id": "cluster_04",
  "replication_status": "replicated",
  "claim_source_sentence": "Here we show that, consistent with this hypothesis, Arky cell activity is selectively enhanced by the Stop! cue, at just the right time to be responsible for Str suppression on correct Stop trials.",
  "replication_evidence_dois": [
    "10.1038/nn.3456",
    "10.1016/j.neuron.2012.04.027"
  ],
  "effect_size_source_sentence": "Stop responses are earlier and stronger in the Arky compared to the Proto subpopulation."
}
source_refs
[
  "paper:paper-89ccc49e1e78"
]
evidence_refs
[
  {
    "ref": "paper:paper-89ccc49e1e78"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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