- claim_text
In mouse prefrontal cortex during reward-anticipation tasks, reward-predictive persistent firing increases arise from sustained increases in mean and variance of membrane potential, persistent decreases in firing are maintained by persistent hyperpolarisation, and these persistent states are layer- and cell-type-specific — present in L5 but not L2/3 pyramidal cells.
- raw_fields
{
"n": 0,
"doi": "10.1016/j.celrep.2021.109082",
"claim": "In mouse prefrontal cortex during reward-anticipation tasks, reward-predictive persistent firing increases arise from sustained increases in mean and variance of membrane potential, persistent decreases in firing are maintained by persistent hyperpolarisation, and these persistent states are layer- and cell-type-specific — present in L5 but not L2/3 pyramidal cells.",
"cite_key": "Kim2021",
"evidence": "",
"effect_size": "",
"text_access": "abstract_only",
"study_system": "mouse PFC pyramidal neurons; in-vivo whole-cell membrane potential recordings during reward-predictive task",
"argument_role": "supporting",
"replication_status": "single_lab",
"claim_source_sentence": "Neurons with persistent depolarization are primarily located in upper L5, whereas those with persistent hyperpolarization are mostly found in lower L5.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": "L2/3 neurons do not show persistent activity."
}- source_refs
[
"paper:paper-c66a21d7dc20"
]
- evidence_refs
[
{
"ref": "paper:paper-c66a21d7dc20"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}