Details

scope
The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism.
claim_text
We found that although the coherence between GP LFPs and mCx ECoG was significantly reduced (Fig. and Supplementary Table ) it was nevertheless not suppressed by STN opto-inhibition.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
effect_size
n = 23
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
We found that although the coherence between GP LFPs and mCx ECoG was significantly reduced (Fig. and Supplementary Table ) it was nevertheless not suppressed by STN opto-inhibition.
study_system
The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism.
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
(, 2020); Crompe B, Aristieta A, Leblois A, Elsherbiny S, Boraud T, Mallet NP.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41467-020-15352-3",
  "claim": "We found that although the coherence between GP LFPs and mCx ECoG was significantly reduced (Fig. and Supplementary Table ) it was nevertheless not suppressed by STN opto-inhibition.",
  "cite_key": "Crompe2020",
  "evidence": " (, 2020); Crompe B, Aristieta A, Leblois A, Elsherbiny S, Boraud T, Mallet NP.",
  "effect_size": "n = 23",
  "text_access": "fulltext",
  "study_system": "The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism.",
  "source_cluster_id": "cluster_13",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found that although the coherence between GP LFPs and mCx ECoG was significantly reduced (Fig. and Supplementary Table ) it was nevertheless not suppressed by STN opto-inhibition.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The β -phase locking of STN neurons was slightly shifted to early phases (Fig. and Supplementary Table ) but most STN neurons were still significantly entrained by β -oscillations ( n = 23/27, Rayleigh test p < 0.05) with a small decrease of both mean phase angles and vector lengths (Supplementary Fig. )."
}
source_refs
[
  "paper:paper-2d3f0b7ed612"
]
evidence_refs
[
  {
    "ref": "paper:paper-2d3f0b7ed612"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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