Version history

{
  "scope": "mouse S1",
  "claim_text": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/nn.4595",
    "year": "2017",
    "claim": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .",
    "title": null,
    "journal": "Nature neuroscience",
    "cite_key": "Cichon2017",
    "evidence": "Activation of cortical somatostatin interneurons prevents the development of neuropathic pain",
    "effect_size": "3-fold",
    "text_access": "fulltext",
    "first_author": "Cichon",
    "study_system": "mouse S1",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "author_list_short": "Cichon, Blanck, Gan",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 25,
    "claim_source_sentence": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "In the region of the S1 corresponding to the injured hind limbs of the animals, we found that Ca 2+ activities in the somata of L5 pyramidal neurons (located > 600 μm below the pial surface) were about 3-fold higher in SNI mice in a quiet resting state than in Sham mice at 1 month post-surgery ( Fig."
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
  "effect_size": "3-fold",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-d00f7f72db9b"
  ],
  "source_span": "Within the S1, there is a large diversity of cortical interneurons including parvalbumin (PV), somatostatin (SOM) and vasoactive intestinal polypeptide (VIP)-expressing neurons 22 .",
  "study_system": "mouse S1",
  "evidence_refs": [
    {
      "ref": "paper:paper-d00f7f72db9b"
    }
  ],
  "section_title": "Local Circuit Motifs and the Disinhibition Framework",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Activation of cortical somatostatin interneurons prevents the development of neuropathic pain",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-07-disinhibition-framework",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_07_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}