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- Live5/17/2026, 4:35:28 PM
62669c924e03Content snapshot
{ "scope": "spiking PFC working memory model", "claim_text": "Spiking working-memory model with strong PV and SST inhibition (and disinhibitory VIP gate) maintains stable temporal dynamics; VIP modulation switches WM into encoding mode.", "raw_fields": { "n": null, "id": "cluster_11_finding_55", "doi": "10.1101/2020.02.11.944751", "pmid": null, "year": "2020", "claim": "Spiking working-memory model with strong PV and SST inhibition (and disinhibitory VIP gate) maintains stable temporal dynamics; VIP modulation switches WM into encoding mode.", "pmcid": null, "title": "Strong inhibitory signaling underlies stable temporal dynamics and working memory in spiking neural networks", "authors": "Kim R, Sejnowski TJ.", "journal": null, "cite_key": "Kim2020", "evidence": "Recurrent spiking PFC model with E/PV/SST/VIP populations; tested working memory robustness under VIP perturbations.", "effect_size": null, "text_access": "abstract_only", "study_system": "spiking PFC working memory model", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 54, "claim_source_sentence": "Dissecting our RNN model revealed strong inhibitory-to-inhibitory connections underlying a disinhibitory microcircuit as a critical component for long neuronal timescales and WM maintenance.", "replication_evidence_dois": [ "10.1016/j.neuron.2023.11.006", "10.1101/2025.05.13.653877", "10.1101/2024.09.30.615819", "10.1016/j.neuron.2018.03.037", "10.1162/netn_a_00427" ], "effect_size_source_sentence": null }, "section_id": "section_12", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-12-computational-models", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-036bff80fcd5" ], "source_span": "Dissecting our RNN model revealed strong inhibitory-to-inhibitory connections underlying a disinhibitory microcircuit as a critical component for long neuronal timescales and WM maintenance.", "study_system": "spiking PFC working memory model", "evidence_refs": [ { "ref": "paper:paper-036bff80fcd5" } ], "section_title": "Computational Models of VIP Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Recurrent spiking PFC model with E/PV/SST/VIP populations; tested working memory robustness under VIP perturbations.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated_independent", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }