- raw_fields
{
"n": 0,
"doi": "10.1523/JNEUROSCI.0500-25.2025",
"claim": "Pathological fast-ripples emerge when perisomatic inhibition from PV+ basket cells collapses, unlike physiological ripples which depend on interneuronal synchrony; fast-ripples result from pyramidal cell pseudosynchrony",
"evidence": "Pathological fast-ripples emerge when perisomatic inhibition from PV+ basket cells collapses, unlike physiological ripples which depend on interneuronal synchrony; fast-ripples result from pyramidal cell pseudosynchrony",
"effect_size": null,
"text_access": "fulltext",
"study_system": "mouse hippocampal slices in vitro, targeted cell-type recordings",
"replication_status": "replication_unknown",
"claim_source_sentence": "We showed that inhibition did not contribute to current and rhythm generation of fast-ripples, unlike physiological ripple oscillations. Instead, pathological fast-ripples emerged when perisomatic inhibition from parvalbumin-expressing basket cells collapsed.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-5ba86585760e"
]
- source_span
We showed that inhibition did not contribute to current and rhythm generation of fast-ripples, unlike physiological ripple oscillations. Instead, pathological fast-ripples emerged when perisomatic inhibition from parvalbumin-expressing basket cells collapsed.
- evidence_refs
[
{
"ref": "paper:paper-5ba86585760e"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}