Details

scope
mouse cortex, Kv3 channel expression
claim_text
Kv3 (Kcnc) channels show highly cell-type-specific expression patterns, with Kv3.1b and Kv3.2 predominating in cortical PV fast-spiking interneurons to enable sub-millisecond repolarization.
section_id
section_02_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
effect_size
Kv3.1b and Kv3.2 enriched in PV fast-spiking cells
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-02
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
study_system
mouse cortex, Kv3 channel expression
section_title
Molecular Identity and Transcriptomic Taxonomy
evidence_summary
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-02
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.0105-09.2009",
  "claim": "Kv3 (Kcnc) channels show highly cell-type-specific expression patterns, with Kv3.1b and Kv3.2 predominating in cortical PV fast-spiking interneurons to enable sub-millisecond repolarization.",
  "evidence": "",
  "effect_size": "Kv3.1b and Kv3.2 enriched in PV fast-spiking cells",
  "text_access": "abstract_only",
  "study_system": "mouse cortex, Kv3 channel expression",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The transcriptional and electrophysiological maturation of neocortical fast-spiking GABAergic interneurons reveals that the electrophysiological properties that distinguish adult cortical cell types emerge relatively late in postnatal development.",
  "replication_evidence_dois": [
    "10.1016/j.cell.2017.08.032"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-591943f1ad14"
]
source_span
The transcriptional and electrophysiological maturation of neocortical fast-spiking GABAergic interneurons reveals that the electrophysiological properties that distinguish adult cortical cell types emerge relatively late in postnatal development.
evidence_refs
[
  {
    "ref": "paper:paper-591943f1ad14"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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