Details

scope
Macaque (27 Macaca fascicularis + 1 Macaca mulatta); fluorescent retrograde tracers; 91-area atlas
claim_text
Quantitative retrograde tracing across 29 macaque cortical areas revealed a high cortico-cortical link density of 66% with 33% unidirectional pathways.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
effect_size
Link density 66%; 33% unidirectional pathways; 1,615 connections
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
Macaque (27 Macaca fascicularis + 1 Macaca mulatta); fluorescent retrograde tracers; 91-area atlas
section_title
Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary
Macaque 29×29 weighted directed connectivity matrix from 28 macaques and a 91-area reference atlas; high density (66%) contradicts earlier sparse Felleman & Van Essen estimates.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 28,
  "doi": "10.1093/cercor/bhs270",
  "claim": "Quantitative retrograde tracing across 29 macaque cortical areas revealed a high cortico-cortical link density of 66% with 33% unidirectional pathways.",
  "cite_key": "Markov2012",
  "evidence": "Macaque 29×29 weighted directed connectivity matrix from 28 macaques and a 91-area reference atlas; high density (66%) contradicts earlier sparse Felleman & Van Essen estimates.",
  "effect_size": "Link density 66%; 33% unidirectional pathways; 1,615 connections",
  "text_access": "fulltext",
  "study_system": "Macaque (27 Macaca fascicularis + 1 Macaca mulatta); fluorescent retrograde tracers; 91-area atlas",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Our analysis of 1615 connections, including 36% that we consider to be NFP, reveals a high density of cortico-cortical connectivity (66%) and an unexpectedly high incidence (33%) of potentially unidirectional pathways, of which one-third (10% of the total) were shown to originate from corresponding areas in the contralateral hemisphere.",
  "replication_evidence_dois": [
    "10.1093/cercor/bhaa060",
    "10.1162/netn_a_00159",
    "10.1162/netn_a_00345"
  ],
  "effect_size_source_sentence": "Our analysis of 1615 connections, including 36% that we consider to be NFP, reveals a high density of cortico-cortical connectivity (66%) and an unexpectedly high incidence (33%) of potentially unidirectional pathways, of which one-third (10% of the total) were shown to originate from corresponding areas in the contralateral hemisphere."
}
source_refs
[
  "paper:paper-cdbcc69b9b9e"
]
source_span
Our analysis of 1615 connections, including 36% that we consider to be NFP, reveals a high density of cortico-cortical connectivity (66%) and an unexpectedly high incidence (33%) of potentially unidirectional pathways, of which one-third (10% of the total) were shown to originate from corresponding areas in the contralateral hemisphere.
evidence_refs
[
  {
    "ref": "paper:paper-cdbcc69b9b9e"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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