Version history

{
  "scope": "basal-ganglia",
  "claim_text": "Leptin acts via lateral hypothalamic neurotensin neurons to inhibit orexin neurons through multiple GABA-independent mechanisms, providing a circuit link between adipocyte-derived energy-status signals and arousal/feeding control in the LHA.",
  "raw_fields": {
    "n": null,
    "doi": "10.1523/jneurosci.5167-13.2014",
    "claim": "Leptin acts via lateral hypothalamic neurotensin neurons to inhibit orexin neurons through multiple GABA-independent mechanisms, providing a circuit link between adipocyte-derived energy-status signals and arousal/feeding control in the LHA.",
    "cite_key": "Goforth2014",
    "evidence": "fulltext_body",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": null,
    "source_cluster_id": "cluster_08",
    "replication_status": "unreplicated",
    "claim_source_sentence": "The adipocyte-derived hormone leptin modulates neural systems appropriately for the status of body energy stores.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_09",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_09_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewLoops",
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  "source_kind": "review_finding",
  "source_path": "evidence/section_09_evidence_package.json",
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    "paper:paper-b28f49fb8c93"
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  "source_span": "The adipocyte-derived hormone leptin modulates neural systems appropriately for the status of body energy stores.",
  "study_system": null,
  "evidence_refs": [
    {
      "ref": "paper:paper-b28f49fb8c93"
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  ],
  "section_title": "The Hypothalamic Extension: Loops for Motivated Behavior",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
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  "replication_status": "unreplicated",
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  "source_artifact_ref": "wiki_page:computationalreviewloops-09",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_09_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
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  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}