Version history

{
  "scope": "review of mouse cortical interneuron taxonomy",
  "claim_text": "5HT3aR-expressing interneurons constitute ~30% of all neocortical INs and form the most heterogeneous of the three principal IN groups (PV, Sst, 5HT3aR); all 5HT3aR INs express functional 5HT3a and nicotinic receptors, conferring strong serotonergic and cholinergic depolarization that gates their firing in vivo.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2016.06.033",
    "claim": "5HT3aR-expressing interneurons constitute ~30% of all neocortical INs and form the most heterogeneous of the three principal IN groups (PV, Sst, 5HT3aR); all 5HT3aR INs express functional 5HT3a and nicotinic receptors, conferring strong serotonergic and cholinergic depolarization that gates their firing in vivo.",
    "title": null,
    "cite_key": "Tremblay2016",
    "evidence": "review/compilation across mouse neocortex; Lee 2010 quantification of 5HT3aR fraction",
    "effect_size": "~30% of cortical INs; universal 5HT3a + nAChR co-expression",
    "text_access": "fulltext",
    "study_system": "review of mouse cortical interneuron taxonomy",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 34,
    "claim_source_sentence": "5HT3aR INs 5HT3aR INs represent ~30% of all neocortical INs and are thought to be more heterogeneous than the PV and Sst groups.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.1869-10.2010"
    ],
    "effect_size_source_sentence": "However, all 5HT3aR INs express functional 5HT3a and nicotinic receptors (Lee et al., 2010)."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "~30% of cortical INs; universal 5HT3a + nAChR co-expression",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-53c8505de50f"
  ],
  "source_span": "5HT3aR INs 5HT3aR INs represent ~30% of all neocortical INs and are thought to be more heterogeneous than the PV and Sst groups.",
  "study_system": "review of mouse cortical interneuron taxonomy",
  "evidence_refs": [
    {
      "ref": "paper:paper-53c8505de50f"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "review/compilation across mouse neocortex; Lee 2010 quantification of 5HT3aR fraction",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}