- claim_text
PV+ inhibitory cells in mouse V1 have synaptic weights specifically tuned to the similarity of connected cells' visual responses, providing tuned feedback inhibition despite dense connectivity that stabilizes feature-specific excitatory ensembles
- raw_fields
{
"n": 0,
"doi": "10.1016/j.neuron.2023.12.013",
"claim": "PV+ inhibitory cells in mouse V1 have synaptic weights specifically tuned to the similarity of connected cells' visual responses, providing tuned feedback inhibition despite dense connectivity that stabilizes feature-specific excitatory ensembles",
"evidence": "In vivo visual responses and synaptic connectivity measurements of PV+ cells in mouse V1",
"effect_size": "Synaptic weights tuned by response similarity; stronger inhibition for co-tuned pairs",
"text_access": "fulltext",
"study_system": "mouse primary visual cortex, in vivo",
"replication_status": "single study",
"claim_source_sentence": "Individual PV+ cells strongly inhibit those pyramidal cells that provide them with strong excitation and share their visual selectivity. This structured organization of inhibitory synaptic weights provides a circuit mechanism for tuned inhibition onto pyramidal cells despite dense connectivity, stabilizing activity within feature-specific excitatory ensembles while supporting competition between them.",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Individual PV+ cells strongly inhibit those pyramidal cells that provide them with strong excitation and share their visual selectivity."
}- source_refs
[
"paper:paper-7ab8027f125a"
]
- source_span
Individual PV+ cells strongly inhibit those pyramidal cells that provide them with strong excitation and share their visual selectivity. This structured organization of inhibitory synaptic weights provides a circuit mechanism for tuned inhibition onto pyramidal cells despite dense connectivity, stabilizing activity within feature-specific excitatory ensembles while supporting competition between them.
- evidence_refs
[
{
"ref": "paper:paper-7ab8027f125a"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}