Version history

{
  "scope": "mouse V1",
  "claim_text": "VIP interneurons, themselves regulated by neuromodulators, may therefore enable selective patterns of activity to propagate through the cortex, by generating a \"spotlight of attention\".<h4>Significance statement</h4>Most inhibitory interneurons have axons restricted to a nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal activity can propagate through cortical circuits.",
  "raw_fields": {
    "n": null,
    "doi": "10.1523/jneurosci.3646-15.2016",
    "year": "2016",
    "claim": "VIP interneurons, themselves regulated by neuromodulators, may therefore enable selective patterns of activity to propagate through the cortex, by generating a \"spotlight of attention\".<h4>Significance statement</h4>Most inhibitory interneurons have axons restricted to a nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal activity can propagate through cortical circuits.",
    "title": null,
    "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience",
    "cite_key": "Karnani2016b",
    "evidence": "Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons",
    "effect_size": null,
    "text_access": "abstract_only",
    "first_author": "Karnani",
    "study_system": "mouse V1",
    "_source_cluster": "cluster_06_disinhibition_circuit",
    "author_list_short": "Karnani, Jackson, Ayzenshtat",
    "replication_status": "replication_unknown",
    "_source_cluster_index": 13,
    "claim_source_sentence": "VIP interneurons, themselves regulated by neuromodulators, may therefore enable selective patterns of activity to propagate through the cortex, by generating a \"spotlight of attention\".<h4>Significance statement</h4>Most inhibitory interneurons have axons restricted to a nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal activity can propagate through cortical circuits.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-0a3cf7627c63"
  ],
  "source_span": "VIP interneurons, themselves regulated by neuromodulators, may therefore enable selective patterns of activity to propagate through the cortex, by generating a \"spotlight of attention\".<h4>Significance statement</h4>Most inhibitory interneurons have axons restricted to a nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal activity can propagate through cortical circuits.",
  "study_system": "mouse V1",
  "evidence_refs": [
    {
      "ref": "paper:paper-0a3cf7627c63"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}