Details

scope
mice, self-paced operant sequence task, recordings in nigrostriatal circuits
claim_text
Nigrostriatal circuits develop start/stop signals that bracket learned action sequences in mice, and disrupting striatal circuits selectively impairs sequence learning and these bracketing signals.
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
effect_size
distinct start vs stop signals emerge during learning
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-04
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
study_system
mice, self-paced operant sequence task, recordings in nigrostriatal circuits
section_title
Striatal Output Pathways: Direct, Indirect, and Beyond
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-04
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1038/nature09263",
  "claim": "Nigrostriatal circuits develop start/stop signals that bracket learned action sequences in mice, and disrupting striatal circuits selectively impairs sequence learning and these bracketing signals.",
  "cite_key": "Jin2010",
  "evidence": "",
  "effect_size": "distinct start vs stop signals emerge during learning",
  "text_access": "abstract_only",
  "study_system": "mice, self-paced operant sequence task, recordings in nigrostriatal circuits",
  "source_cluster_id": "cluster_04",
  "replication_status": "replicated",
  "claim_source_sentence": "Using a self-paced operant task in which mice learn to perform a particular sequence of actions to obtain an outcome, we found neural activity in nigrostriatal circuits specifically signalling the initiation or the termination of each action sequence.",
  "replication_evidence_dois": [
    "10.1016/j.cell.2016.06.032",
    "10.1038/nature17639"
  ],
  "effect_size_source_sentence": "Using a self-paced operant task in which mice learn to perform a particular sequence of actions to obtain an outcome, we found neural activity in nigrostriatal circuits specifically signalling the initiation or the termination of each action sequence."
}
source_refs
[
  "paper:paper-10_1038_nature09263"
]
source_span
Using a self-paced operant task in which mice learn to perform a particular sequence of actions to obtain an outcome, we found neural activity in nigrostriatal circuits specifically signalling the initiation or the termination of each action sequence.
evidence_refs
[
  {
    "ref": "paper:paper-10_1038_nature09263"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.