Version history

{
  "scope": "vip-interneurons",
  "claim_text": "Here, using young adult 3xTg-AD mice, we found that while the density and morphology of I-S3 cells remain unaffected, there were significant changes in their firing output.",
  "raw_fields": {
    "n": null,
    "doi": "10.7554/elife.95412",
    "pmid": "39264364",
    "tags": [
      "snowball_fwd_R2"
    ],
    "year": "2024",
    "claim": "Here, using young adult 3xTg-AD mice, we found that while the density and morphology of I-S3 cells remain unaffected, there were significant changes in their firing output.",
    "pmcid": "PMC11392531",
    "round": 3,
    "title": "Altered firing output of VIP interneurons and early dysfunctions in CA1 hippocampal circuits in the 3xTg mouse model of Alzheimer’s disease",
    "authors": "Félix Michaud; Ruggiero Francavilla; Dimitry Topolnik; Parisa Iloun; Suhel Tamboli; Frédéric Calon",
    "journal": "eLife",
    "citation": "Félix Michaud et al. (2024). eLife. 10.7554/elife.95412",
    "cite_key": "Michaud2024",
    "effect_size": null,
    "text_access": "fulltext",
    "citedByCount": 10,
    "isOpenAccess": "Y",
    "evidence_type": "in_vivo_function",
    "linked_topics": [
      "arousal_state",
      "disease_models",
      "hippocampal_VIP"
    ],
    "_source_cluster": "cluster_07_in_vivo_function",
    "relevance_score": 12.5,
    "replication_status": null,
    "_source_cluster_index": 92,
    "claim_source_sentence": "Here, using young adult 3xTg-AD mice, we found that while the density and morphology of I-S3 cells remain unaffected, there were significant changes in their firing output."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-08-in-vivo-behavior",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-244a49e02ebb"
  ],
  "source_span": "Here, using young adult 3xTg-AD mice, we found that while the density and morphology of I-S3 cells remain unaffected, there were significant changes in their firing output.",
  "study_system": null,
  "evidence_refs": [
    {
      "ref": "paper:paper-244a49e02ebb"
    }
  ],
  "section_title": "In Vivo Function During Behavior",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": null,
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "unevaluated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-08-in-vivo-behavior",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_08_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}