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- Live5/17/2026, 4:35:28 PM
f31ec75b5042Content snapshot
{ "scope": "review of mouse cortical 5HT3aR/Vip taxonomy", "claim_text": "Approximately 40% of cortical 5HT3aR interneurons co-express VIP, while the remaining 5HT3aR neurons (mostly Lamp5/Reelin+) are non-VIP — defining the two principal CGE-derived branches with distinct intrinsic-property repertoires.", "raw_fields": { "n": null, "doi": "10.1016/j.neuron.2016.06.033", "claim": "Approximately 40% of cortical 5HT3aR interneurons co-express VIP, while the remaining 5HT3aR neurons (mostly Lamp5/Reelin+) are non-VIP — defining the two principal CGE-derived branches with distinct intrinsic-property repertoires.", "title": null, "cite_key": "Tremblay2016", "evidence": "review consolidating Lee 2010 and downstream classifications across mouse S1/V1", "effect_size": "VIP+ ≈ 40% of 5HT3aR INs; non-overlapping with PV/Sst", "text_access": "fulltext", "study_system": "review of mouse cortical 5HT3aR/Vip taxonomy", "_source_cluster": "cluster_04_intrinsic_electrophysiology", "replication_status": "replicated", "_source_cluster_index": 33, "claim_source_sentence": "The 5HT3aR group can be divided in two subgroups based on whether or not a 5HT3aR IN expresses vasointestinal pepetide (Vip), which is found in about 40 % of all 5HT3aR INs and is not expressed in PV or Sst neurons (Lee et al., 2010).", "replication_evidence_dois": [ "10.1523/jneurosci.1869-10.2010", "10.1002/dneu.20853" ], "effect_size_source_sentence": "VIP, which is found in about 40 % of all 5HT3aR INs and is not expressed in PV or Sst neurons." }, "section_id": "section_05", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json", "effect_size": "VIP+ ≈ 40% of 5HT3aR INs; non-overlapping with PV/Sst", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology", "source_kind": "review_finding", "source_path": "evidence/section_05_evidence_package.json", "source_refs": [ "paper:paper-53c8505de50f" ], "source_span": "The 5HT3aR group can be divided in two subgroups based on whether or not a 5HT3aR IN expresses vasointestinal pepetide (Vip), which is found in about 40 % of all 5HT3aR INs and is not expressed in PV or Sst neurons (Lee et al., 2010).", "study_system": "review of mouse cortical 5HT3aR/Vip taxonomy", "evidence_refs": [ { "ref": "paper:paper-53c8505de50f" } ], "section_title": "Intrinsic Electrophysiology", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "review consolidating Lee 2010 and downstream classifications across mouse S1/V1", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }