Version history

{
  "scope": "human and mouse models, schizophrenia",
  "claim_text": "NMDA receptor hypofunction may produce PV neuron-mediated inhibition deficits in schizophrenia, but the specific cell types mediating NMDAR dysfunction remain uncertain",
  "raw_fields": {
    "n": 0,
    "doi": "10.1093/schbul/sbs010",
    "claim": "NMDA receptor hypofunction may produce PV neuron-mediated inhibition deficits in schizophrenia, but the specific cell types mediating NMDAR dysfunction remain uncertain",
    "evidence": "Review of NMDAR hypofunction theory as it relates to PV interneurons and gamma oscillations",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "human and mouse models, schizophrenia",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "While dysregulation of NMDARs may play an important role in the pathophysiology of schizophrenia, additional research is required to determine the particular cell type(s) that mediate dysfunctional NMDAR signaling in the illness.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_11_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-11",
  "source_kind": "review_finding",
  "source_path": "evidence/section_11_evidence_package.json",
  "source_refs": [
    "paper:paper-e5b6d90799d6"
  ],
  "source_span": "While dysregulation of NMDARs may play an important role in the pathophysiology of schizophrenia, additional research is required to determine the particular cell type(s) that mediate dysfunctional NMDAR signaling in the illness.",
  "study_system": "human and mouse models, schizophrenia",
  "evidence_refs": [
    {
      "ref": "paper:paper-e5b6d90799d6"
    }
  ],
  "section_title": "Species Translation, Human Data, and Disease Models",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Review of NMDAR hypofunction theory as it relates to PV interneurons and gamma oscillations",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-11",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}