Version history

{
  "scope": "Mouse neocortex",
  "claim_text": "Dose-dependent developmental fluoride exposure leads to neurotoxicity and impairs excitatory synapse development",
  "raw_fields": {
    "n": "n_unknown",
    "doi": "10.1007/s00204-025-04003-5",
    "claim": "Dose-dependent developmental fluoride exposure leads to neurotoxicity and impairs excitatory synapse development",
    "cite_key": "Qiu2025",
    "evidence": "Abstract of Arch Toxicol 2025 paper (PMID 40085203).",
    "effect_size": "",
    "text_access": "abstract_only",
    "study_system": "Mouse neocortex",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Cultured primary embryonic mouse cortical neurons were exposed to varying concentrations of NaF (0-200 μg/ml).",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": ""
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json",
  "effect_size": "",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-5eb0f7c4a288"
  ],
  "source_span": "Cultured primary embryonic mouse cortical neurons were exposed to varying concentrations of NaF (0-200 μg/ml).",
  "study_system": "Mouse neocortex",
  "evidence_refs": [
    {
      "ref": "paper:paper-5eb0f7c4a288"
    }
  ],
  "section_title": "6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Abstract of Arch Toxicol 2025 paper (PMID 40085203).",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}