Details

scope
Mouse neocortex; manually curated tracer-injection corpus aggregated into a cortical connectivity matrix
claim_text
A meta-analysis of >600 anatomical tracer injections across mouse neocortex resolved a cortico-cortical connectivity matrix organized into eight subnetworks.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
effect_size
240 intracortical connections from >600 tracer injections
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
source_span
The connectivity matrices and cortical map revealed that the entire cortex is organized into four somatic sensorimotor, two medial, and two lateral subnetworks that display unique topologies and can interact through select cortical areas.
study_system
Mouse neocortex; manually curated tracer-injection corpus aggregated into a cortical connectivity matrix
section_title
Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary
Manual reconstruction of 240 intracortical connections from >600 tracer experiments yielded a complementary mouse connectome organized into eight functional subnetworks.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 600,
  "doi": "10.1016/j.cell.2014.02.023",
  "claim": "A meta-analysis of >600 anatomical tracer injections across mouse neocortex resolved a cortico-cortical connectivity matrix organized into eight subnetworks.",
  "cite_key": "Zingg2014",
  "evidence": "Manual reconstruction of 240 intracortical connections from >600 tracer experiments yielded a complementary mouse connectome organized into eight functional subnetworks.",
  "effect_size": "240 intracortical connections from >600 tracer injections",
  "text_access": "abstract_only",
  "study_system": "Mouse neocortex; manually curated tracer-injection corpus aggregated into a cortical connectivity matrix",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "The connectivity matrices and cortical map revealed that the entire cortex is organized into four somatic sensorimotor, two medial, and two lateral subnetworks that display unique topologies and can interact through select cortical areas.",
  "replication_evidence_dois": [
    "10.1038/nature13186",
    "10.1038/s41586-019-1716-z"
  ],
  "effect_size_source_sentence": "Over 600 labeled neuronal pathways acquired from tracer injections placed across the entire mouse neocortex enabled us to generate a cortical connectivity atlas."
}
source_refs
[
  "paper:paper-924fdfba1364"
]
evidence_refs
[
  {
    "ref": "paper:paper-924fdfba1364"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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