Details

scope
mouse
claim_text
Oxidative Stress-Induced Damage to the Developing Hippocampus Is Mediated by GSK3β — Neonatal brain injury renders the developing brain vulnerable to oxidative stress, leading to cognitive deficit
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
effect_size
3
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-06-synaptic-properties
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Neonatal brain injury renders the developing brain vulnerable to oxidative stress, leading to cognitive deficit.
study_system
mouse
section_title
Synaptic Properties and Connectivity
evidence_summary
Reported in The Journal of neuroscience : the official journal of the Society for Neuroscience (2022); from Body of abstract.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-06-synaptic-properties
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.2389-21.2022",
  "claim": "Oxidative Stress-Induced Damage to the Developing Hippocampus Is Mediated by GSK3β — Neonatal brain injury renders the developing brain vulnerable to oxidative stress, leading to cognitive deficit",
  "title": null,
  "cite_key": "Abbah2022",
  "evidence": "Reported in The Journal of neuroscience : the official journal of the Society for Neuroscience (2022); from Body of abstract.",
  "effect_size": "3",
  "text_access": "abstract_only",
  "study_system": "mouse",
  "_source_cluster": "cluster_05_synaptic_connectivity",
  "replication_status": "replication_unknown",
  "_source_cluster_index": 320,
  "claim_source_sentence": "Neonatal brain injury renders the developing brain vulnerable to oxidative stress, leading to cognitive deficit.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "With decreased hippocampal levels of Wnt signaling components and somatostatin, HO aberrantly activated glycogen synthase kinase 3 β activity."
}
source_refs
[
  "paper:paper-14f1d0e2a525"
]
evidence_refs
[
  {
    "ref": "paper:paper-14f1d0e2a525"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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