Details

scope
mouse; motor cortex, ALM; silicon-probe recording, computational model; The Journal of neuroscience : the official journal of the Society for Neuroscience
claim_text
Preparatory activity is low-dimensional and monotonic.
section_id
section_09
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
source_kind
review_finding
source_path
evidence/section_09_evidence_package.json
source_span
We find that preparatory activity is low-dimensional and monotonic.
study_system
mouse; motor cortex, ALM; silicon-probe recording, computational model; The Journal of neuroscience : the official journal of the Society for Neuroscience
section_title
9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-09-amplification-isn
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1523/jneurosci.3152-17.2018",
  "claim": "Preparatory activity is low-dimensional and monotonic.",
  "cite_key": "Inagaki2018",
  "evidence": "Neurons in multiple brain regions fire trains of action potentials anticipating specific movements, but this \"preparatory activity\" has not been systematically compared across behavioral tasks. We compared preparatory activity in auditory and tactile delayed-response tasks in male mice. Skilled, directional licking was the motor output. The anterior lateral motor cortex (ALM) is necessary for motor planning in both tasks. Multiple features of ALM preparatory activity during the delay epoch were ...",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse; motor cortex, ALM; silicon-probe recording, computational model; The Journal of neuroscience : the official journal of the Society for Neuroscience",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "We find that preparatory activity is low-dimensional and monotonic.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "claim_rewritten_from_source": true,
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:e8d68957-7c51-41ac-85bd-f5af67fceba1"
]
evidence_refs
[
  {
    "ref": "paper:e8d68957-7c51-41ac-85bd-f5af67fceba1"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}
evidence_summary
Neurons in multiple brain regions fire trains of action potentials anticipating specific movements, but this "preparatory activity" has not been systematically compared across behavioral tasks. We compared preparatory activity in auditory and tactile delayed-response tasks in male mice. Skilled, directional licking was the motor output. The anterior lateral motor cortex (ALM) is necessary for motor planning in both tasks. Multiple features of ALM preparatory activity during the delay epoch were ...

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