Details
- scope
- human postmortem neocortex, schizophrenia
- claim_text
- Phasic synaptic inhibition from specific GABA neuron subtypes including PV cells is essential for synchronized network oscillations, and compensatory responses in schizophrenia are insufficient to restore full gamma power
- section_id
- section_11_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-11
- source_kind
- review_finding
- source_path
- evidence/section_11_evidence_package.json
- source_span
- We suggest that some alterations observed in the neocortex of schizophrenia subjects may be compensatory responses that partially restore inhibitory synaptic efficacy.
- study_system
- human postmortem neocortex, schizophrenia
- section_title
- Species Translation, Human Data, and Disease Models
- evidence_summary
- Review integrating postmortem GABA findings with oscillation neuroscience in schizophrenia
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-11
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_11_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1093/schbul/sbn070", "claim": "Phasic synaptic inhibition from specific GABA neuron subtypes including PV cells is essential for synchronized network oscillations, and compensatory responses in schizophrenia are insufficient to restore full gamma power", "evidence": "Review integrating postmortem GABA findings with oscillation neuroscience in schizophrenia", "effect_size": null, "text_access": "fulltext", "study_system": "human postmortem neocortex, schizophrenia", "replication_status": "independently_replicated", "claim_source_sentence": "We suggest that some alterations observed in the neocortex of schizophrenia subjects may be compensatory responses that partially restore inhibitory synaptic efficacy.", "replication_evidence_dois": [ "10.1016/j.tins.2011.10.004", "10.1016/j.biopsych.2015.03.010" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-7d1f48246bb8" ]
- evidence_refs
[ { "ref": "paper:paper-7d1f48246bb8" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }