Version history

{
  "scope": "Mouse V1 layer 2/3, pulvinar, VIP and SOM interneurons; two-photon imaging + circuit manipulation",
  "claim_text": "Unexpected visual stimuli selectively amplify the responses of the V1 layer 2/3 neurons most tuned to that stimulus — a feature-selective prediction-error signal rather than a generic surprise signal.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41586-024-07851-w",
    "claim": "Unexpected visual stimuli selectively amplify the responses of the V1 layer 2/3 neurons most tuned to that stimulus — a feature-selective prediction-error signal rather than a generic surprise signal.",
    "cite_key": "Furutachi2024",
    "evidence": "Two-photon imaging in mouse V1 with optogenetic and pharmacogenetic manipulation; selective amplification depends on pulvinar input and VIP-mediated disinhibition of a specific SOM subpopulation.",
    "effect_size": "Selective amplification of stimulus-tuned L2/3 neurons (mechanism: pulvinar → VIP → SOM disinhibition gating excitatory pulvinar input)",
    "text_access": "fulltext",
    "study_system": "Mouse V1 layer 2/3, pulvinar, VIP and SOM interneurons; two-photon imaging + circuit manipulation",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "A plausible scenario for how the pulvinar and neocortical VIP neurons interact to mediate prediction-error signals may therefore involve pulvinar input activating VIP neurons in V1, which in turn boost pyramidal neuron responses to unexpected visual stimuli through the VIP–SOM disinhibitory circuit.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1016/j.celrep.2021.109772",
      "10.1093/cercor/bhad163"
    ],
    "effect_size_source_sentence": "In response to prediction errors, VIP neurons inhibit a specific subpopulation of somatostatin-expressing inhibitory interneurons that gate excitatory pulvinar input to V1, resulting in specific pulvinar-driven response amplification of the most stimulus-selective neurons in V1."
  },
  "section_id": "section_14",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json",
  "effect_size": "Selective amplification of stimulus-tuned L2/3 neurons (mechanism: pulvinar → VIP → SOM disinhibition gating excitatory pulvinar input)",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding",
  "source_kind": "review_finding",
  "source_path": "evidence/section_14_evidence_package.json",
  "source_refs": [
    "paper:paper-41aa556ea384"
  ],
  "source_span": "A plausible scenario for how the pulvinar and neocortical VIP neurons interact to mediate prediction-error signals may therefore involve pulvinar input activating VIP neurons in V1, which in turn boost pyramidal neuron responses to unexpected visual stimuli through the VIP–SOM disinhibitory circuit.",
  "study_system": "Mouse V1 layer 2/3, pulvinar, VIP and SOM interneurons; two-photon imaging + circuit manipulation",
  "evidence_refs": [
    {
      "ref": "paper:paper-41aa556ea384"
    }
  ],
  "section_title": "14. Predictive-coding and dynamical-systems accounts — the role of recurrent excitatory feedback in error signalling, state estimation, and reservoir computing, evaluated against mouse data",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon imaging in mouse V1 with optogenetic and pharmacogenetic manipulation; selective amplification depends on pulvinar input and VIP-mediated disinhibition of a specific SOM subpopulation.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}