In macaque, VA, VL and MD basal-ganglia recipient thalamic nuclei project to fr…

In macaque, VA, VL and MD basal-ganglia recipient thalamic nuclei project to frontal cortex via both reciprocal and nonreciprocal connections, with VL targeting caudal motor areas, VA targeting rostral premotor areas, and MD targeting dorsolateral and orbital prefrontal cortex.

{
  "n": 0,
  "doi": "10.1523/jneurosci.22-18-08117.2002",
  "claim": "In macaque, VA, VL and MD basal-ganglia recipient thalamic nuclei project to frontal cortex via both reciprocal and nonreciprocal connections, with VL targeting caudal motor areas, VA targeting rostral premotor areas, and MD targeting dorsolateral and orbital prefrontal cortex.",
  "cite_key": "McFarland2002",
  "evidence": "Bidirectional tracer injections (3H-amino acids, dextran-fluorochromes, WGA) into VA/VL, MD and frontal cortex of macaque mapping reciprocal vs nonreciprocal thalamocortical connections.",
  "effect_size": "Thalamocortical projections concentrate in cortical layers I and III with lesser layer V; layer I projections more extensive than layer III/V in motor areas",
  "text_access": "abstract_only",
  "study_system": "Macaca fascicularis VA/VL/MD–frontal cortex tracing",
  "source_cluster_id": "cluster_05",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "VL projections target caudal motor areas (primary, supplementary, and caudal premotor areas), whereas VA projections target more rostral premotor areas (including cingulate and presupplementary motor areas) and MD projects to dorsolateral and orbital prefrontal cortices.",
  "replication_evidence_dois": [
    "10.1016/j.brainresbull.2008.09.013",
    "10.1002/cne.902420406",
    "10.1002/cne.901710204"
  ],
  "effect_size_source_sentence": "Thalamocortical projections innervate cortical layers I and III, and to a lesser extent, layer V."
}

[
  "paper:paper-1d6c52ded149"
]

VL projections target caudal motor areas (primary, supplementary, and caudal premotor areas), whereas VA projections target more rostral premotor areas (including cingulate and presupplementary motor areas) and MD projects to dorsolateral and orbital prefrontal cortices.

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