Version history

{
  "scope": "human MTG L1; Patch-seq + snRNA-seq",
  "claim_text": "Boldog et al. (2018) identified a human-specific cortical interneuron type ('rosehip cell') in human L1 not matching any mouse Vip/Sst/Pvalb cluster, while several other human L1 t-types (i6, i8, i9, i10, i11) matched mouse Vip+ types, supporting both conserved and human-specific elaboration of CGE-derived interneurons.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41593-018-0205-2",
    "claim": "Boldog et al. (2018) identified a human-specific cortical interneuron type ('rosehip cell') in human L1 not matching any mouse Vip/Sst/Pvalb cluster, while several other human L1 t-types (i6, i8, i9, i10, i11) matched mouse Vip+ types, supporting both conserved and human-specific elaboration of CGE-derived interneurons.",
    "title": null,
    "cite_key": "Boldog2018",
    "evidence": "Patch-seq + snRNA-seq of human L1 cortex; rosehip type lacks mouse homolog; multiple VIP+ L1 clusters share marker signatures with mouse Vip+ types — confirming both conserved CGE-derived VIP types and human-specific innovations.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "human MTG L1; Patch-seq + snRNA-seq",
    "target_section": "section_02",
    "_source_cluster": "cluster_01_molecular_taxonomy",
    "replication_status": "replicated",
    "_source_cluster_index": 33,
    "claim_source_sentence": "Many rosehip marker genes are not expressed in Smad3 or other Pvalb/Sst/Vip-negative mouse cell types or the complete set of mouse GABAergic types. Clusters i6, i8, i9, i11, and i10 matched mouse Vip+ clusters, and cluster i2 matched mouse Sst+ clusters."
  },
  "section_id": "section_02",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-02-classification",
  "source_kind": "review_finding",
  "source_path": "evidence/section_02_evidence_package.json",
  "source_refs": [
    "paper:paper-pm-30150662"
  ],
  "source_span": "Many rosehip marker genes are not expressed in Smad3 or other Pvalb/Sst/Vip-negative mouse cell types or the complete set of mouse GABAergic types. Clusters i6, i8, i9, i11, and i10 matched mouse Vip+ clusters, and cluster i2 matched mouse Sst+ clusters.",
  "study_system": "human MTG L1; Patch-seq + snRNA-seq",
  "evidence_refs": [
    {
      "ref": "paper:paper-pm-30150662"
    }
  ],
  "section_title": "Molecular Identity and Transcriptomic Taxonomy",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Patch-seq + snRNA-seq of human L1 cortex; rosehip type lacks mouse homolog; multiple VIP+ L1 clusters share marker signatures with mouse Vip+ types — confirming both conserved CGE-derived VIP types and human-specific innovations.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-02-classification",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_02_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}