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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse S1", "claim_text": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).", "raw_fields": { "n": null, "doi": "10.1016/j.neuron.2018.10.049", "year": "2019", "claim": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).", "title": null, "journal": "Neuron", "cite_key": "Williams2019", "evidence": "Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition", "effect_size": "p = 0.01", "text_access": "fulltext", "first_author": "Williams", "study_system": "mouse S1", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Williams, Holtmaat", "replication_status": "replication_unknown", "_source_cluster_index": 15, "claim_source_sentence": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).", "replication_evidence_dois": [], "effect_size_source_sentence": "RPS+CNO drives LTP, whereas RPS POm-hM4Di +CNO fails to elicit LTP (p = 0.01)." }, "section_id": "section_12", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "effect_size": "p = 0.01", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-12-computational-models", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-55f18434021b" ], "source_span": "Keywords plasticity long-term potentiation LTP thalamus somatosensory barrel cortex BC disinhibition posterior medial complex of the thalamus POm somatostatin-expressing interneurons SST vasoactive-intestinal-peptide-expressing interneurons VIP parvalbumin-expressing interneurons PV Introduction Sensory experience and perceptual learning can remodel neocortical synaptic circuits throughout life ( Feldman, 2009 ).", "study_system": "mouse S1", "evidence_refs": [ { "ref": "paper:paper-55f18434021b" } ], "section_title": "Computational Models of VIP Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Higher-Order Thalamocortical Inputs Gate Synaptic Long-Term Potentiation via Disinhibition", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }