Details
- scope
- mouse V1 cortex; SMART-seq scRNA-seq + ISH validation
- claim_text
- Tasic et al. (2016) confirmed that the Vip-Chat transcriptomic type uniquely expresses choline acetyltransferase among Vip-positive cells, consistent with previous reports of bipolar VIP/ChAT neurons in upper cortical layers.
- section_id
- section_01
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-01-introduction
- source_kind
- review_finding
- source_path
- evidence/section_01_evidence_package.json
- source_span
- In agreement with previous reports, our Vip-Chat transcriptomic type is located in upper cortical layers, and it displays unique expression of choline acetyltransferase (Chat) in Vip-positive cells.
- study_system
- mouse V1 cortex; SMART-seq scRNA-seq + ISH validation
- section_title
- Introduction
- evidence_summary
- ISH/scRNA-seq co-localization shows Chat expression in upper-layer Vip-Chat cluster cells; consistent with prior reports of cholinergic VIP bipolar interneurons.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-01-introduction
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/nn.4216", "claim": "Tasic et al. (2016) confirmed that the Vip-Chat transcriptomic type uniquely expresses choline acetyltransferase among Vip-positive cells, consistent with previous reports of bipolar VIP/ChAT neurons in upper cortical layers.", "title": null, "cite_key": "Tasic2016", "evidence": "ISH/scRNA-seq co-localization shows Chat expression in upper-layer Vip-Chat cluster cells; consistent with prior reports of cholinergic VIP bipolar interneurons.", "effect_size": null, "text_access": "fulltext", "study_system": "mouse V1 cortex; SMART-seq scRNA-seq + ISH validation", "target_section": "section_11", "_source_cluster": "cluster_01_molecular_taxonomy", "replication_status": "replicated", "_source_cluster_index": 2, "claim_source_sentence": "In agreement with previous reports, our Vip-Chat transcriptomic type is located in upper cortical layers, and it displays unique expression of choline acetyltransferase (Chat) in Vip-positive cells." }- source_refs
[ "paper:paper-ed2a7f08ef35" ]
- evidence_refs
[ { "ref": "paper:paper-ed2a7f08ef35" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }