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- Live5/17/2026, 4:35:28 PM
3f4c755155c5Content snapshot
{ "scope": "Awake mouse visual cortex, 2P calcium imaging", "claim_text": "A new dynamic Zebra-noise stimulus combined with a wavelet-based analysis model enables rapid characterization of position, orientation, size, spatial frequency, drift rate and direction tuning for thousands of mouse-V1 neurons in just five minutes of stimulus (repeated three times) using two-photon calcium imaging — significantly extending the throughput envelope of feature-tuning measurements in mouse cortex.", "raw_fields": { "n": 0, "doi": "10.1167/jov.26.1.1", "claim": "A new dynamic Zebra-noise stimulus combined with a wavelet-based analysis model enables rapid characterization of position, orientation, size, spatial frequency, drift rate and direction tuning for thousands of mouse-V1 neurons in just five minutes of stimulus (repeated three times) using two-photon calcium imaging — significantly extending the throughput envelope of feature-tuning measurements in mouse cortex.", "cite_key": "Skriabine2026", "evidence": "Stimulus + wavelet model comparison vs traditional stimuli; thousand-neuron-scale tuning measurements in mouse V1.", "effect_size": "thousands of neurons tuned across 6 stimulus dimensions in 5 min × 3 repeats", "text_access": "fulltext", "study_system": "Awake mouse visual cortex, 2P calcium imaging", "argument_role": "supporting", "replication_status": "single-study-methods", "claim_source_sentence": "The method proved efficient, requiring only 5 minutes of stimulus (repeated three times) to characterize the tuning of thousands of neurons across visual areas.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "The method proved efficient, requiring only 5 minutes of stimulus (repeated three times) to characterize the tuning of thousands of neurons across visual areas." }, "section_id": "section_16", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json", "effect_size": "thousands of neurons tuned across 6 stimulus dimensions in 5 min × 3 repeats", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-16-synthesis", "source_kind": "review_finding", "source_path": "evidence/section_16_evidence_package.json", "source_refs": [ "paper:paper-e3ab0a91f3c5" ], "source_span": "The method proved efficient, requiring only 5 minutes of stimulus (repeated three times) to characterize the tuning of thousands of neurons across visual areas.", "study_system": "Awake mouse visual cortex, 2P calcium imaging", "evidence_refs": [ { "ref": "paper:paper-e3ab0a91f3c5" } ], "section_title": "16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Stimulus + wavelet model comparison vs traditional stimuli; thousand-neuron-scale tuning measurements in mouse V1.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single-study-methods", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-16-synthesis", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }