Details
- scope
- mouse medial prefrontal cortex slices, in vitro
- claim_text
- In the PING model, pyramidal cells driven by asynchronous excitatory input recruit PV fast-spiking interneurons, which then synchronize the PCs via feedback inhibition to generate gamma oscillations
- section_id
- section_07_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
- effect_size
- Carbachol increased firing probability per gamma cycle for both PCs and FSNs
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-07
- source_kind
- review_finding
- source_path
- evidence/section_07_evidence_package.json
- source_span
- In PING oscillations, pyramidal cells (PCs), driven by asynchronous excitatory input, recruit parvalbumin-positive fast-spiking interneurons (FSNs), which then synchronize the PCs via feedback inhibition.
- study_system
- mouse medial prefrontal cortex slices, in vitro
- section_title
- Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
- evidence_summary
- Analysis of cholinergic modulation effects on PING model circuit components in mPFC brain slices
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-07
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1113/jphysiol.2013.253823", "claim": "In the PING model, pyramidal cells driven by asynchronous excitatory input recruit PV fast-spiking interneurons, which then synchronize the PCs via feedback inhibition to generate gamma oscillations", "evidence": "Analysis of cholinergic modulation effects on PING model circuit components in mPFC brain slices", "effect_size": "Carbachol increased firing probability per gamma cycle for both PCs and FSNs", "text_access": "fulltext", "study_system": "mouse medial prefrontal cortex slices, in vitro", "replication_status": "independently replicated", "claim_source_sentence": "In PING oscillations, pyramidal cells (PCs), driven by asynchronous excitatory input, recruit parvalbumin-positive fast-spiking interneurons (FSNs), which then synchronize the PCs via feedback inhibition.", "replication_evidence_dois": [ "10.1146/annurev-neuro-062111-150444" ], "effect_size_source_sentence": "Interestingly, when PCs or FSNs fired in response to gamma frequency oscillatory inputs, CCh increased the firing probability per cycle." }- source_refs
[ "paper:paper-5455b30b1799" ]
- evidence_refs
[ { "ref": "paper:paper-5455b30b1799" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }