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- Live5/17/2026, 4:35:28 PM
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{ "scope": "rat neocortex", "claim_text": "Using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-3) interneurons and L5 pyramidal neurons in the rat neocortex.", "raw_fields": { "n": null, "doi": "10.1038/nn.3305", "year": "2013", "claim": "Using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-3) interneurons and L5 pyramidal neurons in the rat neocortex.", "title": null, "journal": "Nature neuroscience", "cite_key": "Jiang2013", "evidence": "The organization of two new cortical interneuronal circuits", "effect_size": "1% of", "text_access": "abstract_only", "first_author": "Jiang", "study_system": "rat neocortex", "_source_cluster": "cluster_06_disinhibition_circuit", "author_list_short": "Jiang, Wang, Lee", "replication_status": "replicated", "_source_cluster_index": 9, "claim_source_sentence": "Using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-3) interneurons and L5 pyramidal neurons in the rat neocortex.", "replication_evidence_dois": [ "10.3389/fncir.2016.00076" ], "effect_size_source_sentence": "L1 single-bouquet cells (SBCs) preferentially formed unidirectional inhibitory connections on L2/3 interneurons that inhibited the entire dendritic-somato-axonal axis of ∼1% of L5 pyramidal neurons located in the same column." }, "section_id": "section_13", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "effect_size": "1% of", "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-13-conclusion", "source_kind": "review_finding", "source_path": "evidence/section_13_evidence_package.json", "source_refs": [ "paper:paper-1080610ac8ac" ], "source_span": "Using simultaneous quadruple-octuple in vitro and dual in vivo whole-cell recordings, we found two previously unknown interneuronal circuits that link cortical layer 1-3 (L1-3) interneurons and L5 pyramidal neurons in the rat neocortex.", "study_system": "rat neocortex", "evidence_refs": [ { "ref": "paper:paper-1080610ac8ac" } ], "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "The organization of two new cortical interneuronal circuits", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }