Optogenetic inactivation of mPFC VIP cells during the delay period reduces choi…

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scope: vip-interneurons
claim_text: Optogenetic inactivation of mPFC VIP cells during the delay period reduces choice accuracy, supporting causal involvement in memory-guided behavior.
section_id: section_09
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-09-cross-areas
source_kind: review_finding
source_path: evidence/section_09_evidence_package.json
source_span: Optogenetic inactivation experiments were performed using PV-Cre, SST-Cre, VIP-Cre mice injected with AAV2-CAG-FLEX-ArchT-tdTomato, and PV-Halo mice (PV-Cre mice crossed with loxP-flanked-Halo-EYFP mice (014539)).
section_title: VIP Interneurons Across Brain Regions
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: unevaluated
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-09-cross-areas
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_09_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (4)

raw_fields

{
  "n": null,
  "doi": "10.1038/nn.4554",
  "year": "2017",
  "claim": "Optogenetic inactivation of mPFC VIP cells during the delay period reduces choice accuracy, supporting causal involvement in memory-guided behavior.",
  "title": null,
  "region": "mPFC",
  "cite_key": "Kamigaki2017",
  "effect_size": null,
  "text_access": "fulltext",
  "conflict_flag": false,
  "fig_table_ref": null,
  "_source_cluster": "cluster_08_brain_regions",
  "evidence_gap_flag": false,
  "unreplicated_flag": false,
  "replication_status": null,
  "_source_cluster_index": 69,
  "claim_source_sentence": "Optogenetic inactivation experiments were performed using PV-Cre, SST-Cre, VIP-Cre mice injected with AAV2-CAG-FLEX-ArchT-tdTomato, and PV-Halo mice (PV-Cre mice crossed with loxP-flanked-Halo-EYFP mice (014539))."
}

source_refs

[
  "paper:paper-6552e7a00e2e"
]

evidence_refs

[
  {
    "ref": "paper:paper-6552e7a00e2e"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

Optogenetic inactivation of mPFC VIP cells during the delay period reduces choi…

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