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- Live5/17/2026, 4:35:28 PM
fe80d9ee275aContent snapshot
{ "scope": "10 rhesus macaques (DWI) compared against CoCoMac and Markov-Kennedy retrograde tracing datasets", "claim_text": "Diffusion-MRI streamline counts (NOS) in macaque correlate positively with retrograde-tract-tracing FLNe but underestimate the dynamic range of true axonal connectivity weights, indicating that diffusion tractography captures connectome topology with reduced quantitative weight resolution relative to anatomical tracing.", "raw_fields": { "n": 0, "doi": "10.1002/hbm.22828", "claim": "Diffusion-MRI streamline counts (NOS) in macaque correlate positively with retrograde-tract-tracing FLNe but underestimate the dynamic range of true axonal connectivity weights, indicating that diffusion tractography captures connectome topology with reduced quantitative weight resolution relative to anatomical tracing.", "cite_key": "VandenHeuvel2015", "evidence": "Diffusion-MRI streamline counts (NOS) in macaque correlate positively with retrograde-tract-tracing FLNe but underestimate the dynamic range of true axonal connectivity weights, indicating that diffusion tractography captures connectome topology with reduced quantitative weight resolution relative to anatomical tracing.", "effect_size": null, "text_access": "fulltext", "study_system": "10 rhesus macaques (DWI) compared against CoCoMac and Markov-Kennedy retrograde tracing datasets", "source_cluster_id": "cluster_07", "replication_status": "replication_unknown", "claim_source_sentence": "In the field of human macroconnectomics the number of reconstructed fiber streamlines (NOS) is more and more used as a metric of cortico-cortical interareal connectivity strength, but the link between DWI NOS and in vivo animal tract-tracing measurements of anatomical connectivity strength remains poorly understood.", "replication_evidence_dois": [], "effect_size_source_sentence": null }, "section_id": "section_08", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewLoops", "section_ref": "wiki_page:computationalreviewloops-08", "source_kind": "review_finding", "source_path": "evidence/section_08_evidence_package.json", "source_refs": [ "paper:paper-9fcd61fe4817" ], "source_span": "In the field of human macroconnectomics the number of reconstructed fiber streamlines (NOS) is more and more used as a metric of cortico-cortical interareal connectivity strength, but the link between DWI NOS and in vivo animal tract-tracing measurements of anatomical connectivity strength remains poorly understood.", "study_system": "10 rhesus macaques (DWI) compared against CoCoMac and Markov-Kennedy retrograde tracing datasets", "evidence_refs": [ { "ref": "paper:paper-9fcd61fe4817" } ], "section_title": "Cortical Association Connectome: Intra-Cortical Loops and Modules", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }, "evidence_summary": "Diffusion-MRI streamline counts (NOS) in macaque correlate positively with retrograde-tract-tracing FLNe but underestimate the dynamic range of true axonal connectivity weights, indicating that diffusion tractography captures connectome topology with reduced quantitative weight resolution relative to anatomical tracing.", "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d49e54403ef9", "source_artifact_ref": "wiki_page:computationalreviewloops-08", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_08_evidence_package.json", "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }