Details

scope
10 ex vivo rhesus macaque brains compared against CoCoMac + Markov tract-tracing datasets
claim_text
In macaque, dMRI tractography number-of-streamlines correlates positively with retrograde tract-tracing FLN-based connection strengths from CoCoMac and Markov datasets (P<0.001).
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
effect_size
P < 0.001 correlation between DWI NOS and tract-tracing connection strength
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-12
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
10 ex vivo rhesus macaque brains compared against CoCoMac + Markov tract-tracing datasets
section_title
Whole-Brain Connectomics: Mouse, Primate, Human
evidence_summary
Cross-validation of in vivo DWI-derived connectivity weights against gold-standard macaque tract-tracing data.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-12
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_12_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (5)
raw_fields
{
  "n": 10,
  "doi": "10.1002/hbm.22828",
  "claim": "In macaque, dMRI tractography number-of-streamlines correlates positively with retrograde tract-tracing FLN-based connection strengths from CoCoMac and Markov datasets (P<0.001).",
  "cite_key": "VandenHeuvel2015",
  "evidence": "Cross-validation of in vivo DWI-derived connectivity weights against gold-standard macaque tract-tracing data.",
  "effect_size": "P < 0.001 correlation between DWI NOS and tract-tracing connection strength",
  "text_access": "abstract_only",
  "study_system": "10 ex vivo rhesus macaque brains compared against CoCoMac + Markov tract-tracing datasets",
  "source_cluster_id": "cluster_11",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "NOS and density of reconstructed fiber pathways derived from DWI data acquired across 10 rhesus macaques was found to positively correlate to tract-tracing based measurements of connectivity strength across both the CoCoMac and Markov dataset (both P < 0.001), suggesting DWI NOS to form a valid method of assessment of the projection strength of white matter pathways.",
  "replication_evidence_dois": [
    "10.1162/netn_a_00098",
    "10.1038/s41467-017-01285-x"
  ],
  "effect_size_source_sentence": "NOS and density of reconstructed fiber pathways derived from DWI data acquired across 10 rhesus macaques was found to positively correlate to tract-tracing based measurements of connectivity strength across both the CoCoMac and Markov dataset (both P < 0.001), suggesting DWI NOS to form a valid method of assessment of the projection strength of white matter pathways."
}
source_refs
[
  "paper:paper-9fcd61fe4817"
]
source_span
NOS and density of reconstructed fiber pathways derived from DWI data acquired across 10 rhesus macaques was found to positively correlate to tract-tracing based measurements of connectivity strength across both the CoCoMac and Markov dataset (both P < 0.001), suggesting DWI NOS to form a valid method of assessment of the projection strength of white matter pathways.
evidence_refs
[
  {
    "ref": "paper:paper-9fcd61fe4817"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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