Version history

{
  "scope": "cortical model of PV-mediated gamma oscillation plasticity",
  "claim_text": "Gamma oscillation plasticity is mediated by parvalbumin interneurons, with computational modeling showing how PV–SST/VIP interactions set learning-induced oscillation states.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_155",
    "doi": "10.1126/sciadv.adj7427",
    "pmid": "38295164",
    "year": "2024",
    "claim": "Gamma oscillation plasticity is mediated by parvalbumin interneurons, with computational modeling showing how PV–SST/VIP interactions set learning-induced oscillation states.",
    "pmcid": "PMC10830109",
    "title": "Gamma oscillation plasticity is mediated via parvalbumin interneurons",
    "authors": "Hadler MD, Tzilivaki A, Schmitz D, Alle H, Geiger JRP.",
    "journal": "Science Advances",
    "cite_key": "Hadler2024",
    "evidence": "Authors developed a cortical model of PV-mediated gamma oscillation plasticity and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.",
    "vip_role": "oscillations",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "cortical model of PV-mediated gamma oscillation plasticity",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 154,
    "claim_source_sentence": "A microcircuit computational model of CA3 gamma oscillations predicts CP-AMPAR plasticity onto PVIs critically outperforms pyramidal cell plasticity in increasing gamma power and completely accounts for gamma potentiation.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_13",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "source_kind": "review_finding",
  "source_path": "evidence/section_13_evidence_package.json",
  "source_refs": [
    "paper:paper-058858c072a9"
  ],
  "source_span": "A microcircuit computational model of CA3 gamma oscillations predicts CP-AMPAR plasticity onto PVIs critically outperforms pyramidal cell plasticity in increasing gamma power and completely accounts for gamma potentiation.",
  "study_system": "cortical model of PV-mediated gamma oscillation plasticity",
  "evidence_refs": [
    {
      "ref": "paper:paper-058858c072a9"
    }
  ],
  "section_title": "Synthesis and Conclusion: Reassessing the Canonical VIP Disinhibitor",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Authors developed a cortical model of PV-mediated gamma oscillation plasticity and report VIP-related disinhibition / interneuron-circuit dynamics consistent with the canonical VIP→SST→pyramidal motif.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-13-conclusion",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_13_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}